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Antibiotic resistance HGT


Antibiotic resistance HGT program allows you to identify horizontal transfers of antibiotic resistance genes between bacteria. All the data are taken from ARDB - Antibiotic Resistance Genes Database.

You have to select an antibiotic, a corresponding antibiotic resistance gene and the list of species (at least 4). The program will infer a species tree (using the GenBank taxonomy) and a gene tree (using GenBank and accession numbers from ARDB). The gene tree sequences are aligned using MUSCLE and the gene tree is inferred using RAxML. The HGT-Detection algorithm (Boc et al. 2010) is then used to infer horizontal gene transfers.

This program was developed by Nail Amine Chabane, Sofiane Amir Reda Tighilt and Vladimir Makarenkov.

This site has been visited 2550399 times since Friday, November 25, 2005.

Boc, A., Diallo, Alpha B. and Makarenkov, V. (2012), T-REX: a web server for inferring, validating and visualizing phylogenetic trees and networks, Nucleic Acids Research, 40(W1), W573-W579.

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